DFG Collaborative Research Centre 1444
The Collaborative Research Centre 1444 Directed Cellular Self‐Organisation to Advance Bone Regeneration aims to unravel the basic mechanisms that differentiate between success and failure in regeneration of musculoskeletal tissue using bone healing as a role model.
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Doctoral Researcher of the CRC 1444
Correlative approach to study endothelial junction architecture and sprouting angiogenesis in iPSC-derived endothelial cells for different disease models
Resolving the Activin A receptor complex and its endothelial function in Fibrodysplasia Ossificans Progressiva (FOP)
In silico Investigation of the Mechano-Regulation of Sprouting Angiogenesis during Bone Healing
Shaping the inflammatory injury response: Clinical validation of Iloprost as a local immune modulation strategy to enhance bone regeneration - IloBone a phase I/IIa study
Next generation MSCs for regenerative purposes - manipulation of the cellular phenotype using biomaterials and non-viral gene transfer
Development of in vivo fluorescence lifetime imaging techniques for analyzing the immunometabolism during bone healing
ILC and bone metabolism during pregnancy
Extracellular matrix coding and reading: Alterations under compromised conditions and consequences for cell behavior in tissue regeneration
Anisotropic hydrogels with patterns in degradation to modulate hMSCs differentiation
Epigenetically imprinted senescence in T lymphocytes
Deciphering the brain integrity and modulation of endothelial cell junctions under the control of BMP
Regulation of Osteoclastogenesis by the DNA Damage Response
Investigates the dynamics of the ECM and vascular system during bone healing at the cellular level
Examines crosstalk of endothelial cells and pericytes in vitro and on-a-chip with a focus on mechano-transducers YAP and TAZ
The role of ILC in vascular function and angiogenesis
Deep cellular and molecular phenotyping of T lymphocytes
3D Assessment of multi-body dynamics using bi-planar video-fluoroscopy
Analyse des Stromakompartiments im Knochenmark bei der Knochenheilung
Understanding the molecular and genetic basis of vascular diseases using in-vitro models
3D analysis of vascularization and the interaction between macrophages and endothelial cells during fracture healing
Regulatory T cells - the role of phenotypical properties during bone healing and regeneration
Ilobone Study
Metabolic alterations in fibroblast subsets during early bone regeneration: Successful versus delayed healing
Understanding the metabolic adaptation of immune cells during bone regeneration
Understand and reshape the impact of obesity/type 2 diabetes mellitus and adaptive immunity on bone fracture healing
Chromatin organization and gene regulation under physical forces of fluid shear stress in the vascular system
Pathophysiology of multiple trauma: the interaction between traumatic brain injury, spinal cord injury, and bone fracture - studies on adrenergic regulation and energy metabolism
Impact of nutrient regulation on bone-resident progenitor cells, bone marrow adipogenesis and bone health
Biochemical and functional characterisation of bone regenerative marrow adipose tissue
The effect of osmotic pressure on tissue growth
The effect of a-CGRP on cells involved in bone healing
Mechanism of Regenerative Cell Action in Osteoarthritis
