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01.01.2023 To 31.12.2023

CRC 1444 Wolff Lecture Series 2023

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Event for expert public only

For the CRC 1444 community

As part of the Julius Wolff Lecture, the scientists of the CRC network report on the latest results and developments within the framework of the Collaborative Research Centre 1444.

Here the PIs of the CRC projects are presenting their research work that inspired their projects within the CRC. Thus junior scientists within the SFB will learn about the research background of all PIs and simultaneously gain a vast background around the CRC topic of “Directed Cellular Self-Organisation for Advancing Bone Regeneration”. Within this series of talks the scientific advisory board of the CRC is also invited to give talks, thus experts of the field are being heard. During the following years young scientists and further invited speaker will provide a multitude of topics for the CRC research community. Talks are being held online and lively discussions follow each talk providing the necessary exchange within our CRC community and giving young scientist the opportunity to gain experience and expertise.

Organizational and administrative matters


Katharina Schmidt-Bleek : IL-5 a new switchman of the railway line to successful bone regeneration
Norman Drzeniek: Controlling the immunogenicity of IL-10 mRNA for immune modulatory applications

Julia Polansky & Dieter Volk: Effector T cell subsets revisited

Lion Raaz, Jerome Jatzlau, Paul Mendez: Fluid shear stress dependent modulation of endothelial chromatin accessibility

Stefanie Donner & Lea Heinemann: Metallionen-Analyse der Synovialflüssigkeit als Hinweis auf eine lokale Gewebereaktion

Adam Trepczynski: Impact of overall anatomy and kinematics on internal loading in femur and tibia Mark Heyland: Retrospective analysis of clinical cases: Mechanical parameters vs. healing
Marko Leskovar: Experimentally measuring internal interfragmentary movements in situ

Rebecca Günther: “Extracellular matrix coding and reading: Alterations under compromised conditions and consequences for cell behavior in tissue regeneration” Mounir Benamar: BMPR2 regulates endothelial tip-cell filopodia formation and pulling during sprouting angiogenesis”
Claudia Andrea Garrido Gutiérrez: Anisotropic 3D hydrogels with patterns in degradation modulate hMSC differentiation

Julia Mehl: Angiogenesis and extracellular matrix assembly in bone healing and bone growth
Katharina Koch: Mechanocrines – YAP/TAZ dependent endothelial paracrine signaling

Chiara Dazzi: In silico investigation on the role of the outer-vascular mechanics during sprouting angiogenesis
Erik Brauer: Changes in age-related cell mechanics and its impact on vascular sprouting

Asylkhan Rakhymzhan: Intravital three-photon imaging of intact murine tibia: analyzing cell dynamics and function in long bones
Alexander Fiedler: Metabolic imaging in vivo reveals heterogeneity in myeloid cells during bone regeneration

Katharina Schmidt-Bleek: Adiponektin and Bone Healing
Charlotte Rinne: Impact of nutrition on bone health and stem cell-based bone formation
George Soultoukis: Impact of nutrition on bone health and stem cell-based bone formation

Hülya Zeynep Oktay: Understanding the metabolic adaptation of immune cells during bone regeneration, Anne Noom: Cellular metabolism and myofibroblast contraction

Ulrike Weichelt: Effect of traumatic brain injury and traumatic spinal cord injury on energy distribution, adrenergic signaling and bone regeneration

Antigoni Triantafyllopoulou: Macrophage and osteoclast regulation by innate immunity and the DNA damage response

Ioanna Maria Dimitriou: P16 & IloBone: Updates from the clinic and the lab

Duda, Beule, Stöckle

Zaslansky & Fratzl

Event organizer





BIH - Julius Wolff Institut
Charité - Universitätsmedizin Berlin
Augustenburger Platz 1
13353 Berlin

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