PD Dr. Katharina Schmidt-Bleek
CRC 1444 Deputy Scientific Coordinator & Implementation of 3R principles, Subprojects 1 & 12 | RU 2165 Subprojects 5 & 6Charité - Universitätsmedizin Berlin
Julius Wolff Institut
Föhrer Str. 15
13353 Berlin
Campus / internal address:
Südstraße 2
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Expertise
In her research, Dr. rer. nat Katharina Schmidt-Bleek aims to unravel the regeneration capacity of bone tissue. This research area allows her to combine her two university qualifications, molecular medicine and veterinary medicine, to study the organ system “bone” in vitro and in vivo. She is specifically interested in the interaction between the musculoskeletal and the immune system with a particular focus on the adaptive immune system.
The complex processes of bone healing, adaptation and homeostasis offer a multitude of fascinating research approaches, which address the currently unmet clinical needs in the field of bone healing. Especially the demographic changes with an increasingly aged population generates more need for knowledge in this clinical field. Particularly the emerging field of osteoimmunology offers promising therapeutic approaches in this respect. The need for basic research knowledge for the development of such therapeutic approaches is central to the research group of Katharina Schmidt-Bleek.
Additional information
Member of the Steering committee of the CRC 1444
Deputy Scientific Coordinator &
Implementation of 3R principles
Publications in the framework of the RU 2165 and the CRC 1444
Burkhardt et al. Front. Cell Dev. Biol. 2023
Drzeniek et al. Biomaterials 2023
Duda et al. Nat. Rev. Rheumatol. 2023
Bucher et al. Exp. Mol. Med. 2022
Schlundt et al Acta Biomater. 2021
Schlundt et al Front. Immunol. 2019
Bucher et al Front. Immunol. 2019
Wendler et al Front. Immunol. 2019
Sbierski-Kind et al J. Vis. Exp. 2019
Sbierski-Kind et al Front. Immunol. 2018
El-Khassawna et al Front. Immunol. 2017
Sass et al J. Bone Miner. Res. 2017
Lei et al Front. Pharmacol. 2015
Patente im Rahmen der FOR 2165
EP3675909 - Immunmodulation for prevention of poor healing of musculoskeletal injuries in compromised patients
EP3631450 - CD8 T cell subsets as a biomarker for predicting non-fusion after spinal fusion surgery
EP3254697 - Means for treating delayed fracture healing
EP2810065 - CD8+ T-cell subsets as markers for prediction of delayed fracture healing
Vita PD Dr. Katharina Schmidt-Bleek
Professional Development
- December 2019
Habilitation - Since 2016
Head of the Research Facility “Advanced Animal Models” - Since 2012
Research Group Leader “Biology of Bone Healing” - 2012
Veterinarian for Laboratory Animal Science - Since 2010
Prinzipal Investigator “Osteoimmunology” - Since 2006
Veterinarian and Postdoctoral Research Fellow at the Julius Wolff Institute and Center for Musculoskeletal Research Charité – Universitätsmedizin Berlin - April 2006
Approbation - 1999 – 2006
Study of Veterinary Medicine, Freie Universität Berlin - Juni 1997
Dissertation, Freie Universität Berlin - 1994 – 1997
Doctoral Thesis in Molecularbiology, Institut für Genbiologische Forschung Berlin GmbH - 1993
Diploma in Biology - 1987 – 1993
Study of Biology, Universität Kaiserslautern and Universität Hamburg
Scientific Development
- Seit Dez 2006
Veterinarian and Postdoctoral Fellow, Julius Wolff Institute, Charité - 1994 – 1997
Postdoctoral Fellow, Institut für Genbiologische Forschung Berlin GmbH
Functions / offices
Professional Affiliations
- DGOU – Deutsche Gesellschaft für Orthopädie und Unfallchirurgie
- European Calcified Tissue Society
- International Society for Fracture Repai
- ORS – Orthopaedic Research Society
Reviewer for
- DFG- Deutsche ForschungsgemeinschaftJournal of Orthopeadic Researche
- Cells & Materials Journal
- Journal of Orthopaedic Trauma
- Tissue Engineering: Parts A, B, & C
- Veterinary and Comparative Orthopaedics and TraumatologyJournal of Biomechanics
- Bone
Teaching
- BSRT Course Preclinical Studies I: Animal experiments in science
- Practical Course on "Bone healing models and monitoring"
- FELASA A and C course
Organizer of
- Immune modulation as therapeutical strategy in bone regeneration; ORS workshop, New Orleans 2014
- ISBR – International Symposium on Bone Regeneration, Berlin 2015
- The good and the bad - interdependency of bone and immune cells: Possibilities for future treatments?; ORS workshop, Disney's Coronado Springs Resort 2016
