Research Unit 2165
The Research Unit 2165 Regeneration in Aged Individuals: Using Bone Healing as a Model System to Characterise Regeneration under Compromised Conditions aims to understand the basic mechanisms that impede the otherwise effective healing process along the two pathways of early immune response and restoration of mechanical competence through aging.
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Regeneration in Aged Individuals: Using Bone Healing as a Model System to Characterise Regeneration under Compromised Conditions
Regenerative medicine aims at completely restoring tissue structure and function by supporting endogenous regeneration. While regenerative therapies gain more and more attention as innovative therapeutic opportunities, it is essential to identify the road blocks or deficits impairing healing processes in general and specifically in patients that have unmet clinical needs. Regenerative medicine may present solutions for some of those unmet clinical needs; with most therapeutic challenges existing in aged or otherwise compromised patients. Aging appears to substantially alter healing. This alteration in healing cascades is not yet understood. A basic understanding on how endogenous healing is influenced by aging is essential for the successful implementation of regenerative medicine approaches to relevant patient groups.