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Research Unit 2165

The Research Unit 2165 Regeneration in Aged Individuals: Using Bone Healing as a Model System to Characterise Regeneration under Compromised Conditions aims to understand the basic mechanisms that impede the otherwise effective healing process along the two pathways of early immune response and restoration of mechanical competence through aging. 

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Completed doctorates

Erik Brauer

Doctoral projekt: Molecular crosstalk between BMP growth factor signalling and mechanical loading during the early phase of fracture healing

Supervisors of the RU 2165: DudaKnausPetersen

Dissertation: Deutsche Natonalbibliothek

Christian Bucher

Promotionsprojekt: Bone tissue under the influence of an aged/experienced adaptive immune system

Supervisors of the RU 2165: DudaVolk | Schmidt-Bleek

Dissertation: Deutsche Nationalbibliothek

Lisa Burkhardt

Doctoral projekt: Adipogenic/osteogenic lineage differentiation of stem cells influences the healing process of bone fractures and is steered by the immune reaction

Supervisors of the RU 2165: DudaSchmidt-BleekSchulz

Dissertation: Deutsche Nationalbibliothek

Sophie Görlitz

Doctoral projekt: The role of mechanical forces in osteogenic differ-entiation, BMP signaling and early tissue formation processes in the context of bone healing

Supervisors of the RU 2165: DudaKnausPetersen

Dissertation: Deutsche National Bibliothek

Mark Heyland

Doctoral projekt: Mechanotherapy ob Bone Fracture: Adapted fixa-tion conditions

Supervisor of the RU 2165: Duda

Dissertation: Deutsche National Bibliothek

Jerome Jatzlau

Doctoral projekt: Guiding BMP signalling: UNC5B as arterial BMP co-receptor

Supervisor of the RU 2165: Knaus

Dissertation: Deutsche National Bibliothek

Daniela Keller

Promotionsprojekt: The role of cellular senescence in bone homeosta-sis and regeneration

Supervisors of the RU 2165: KornakGeißler

Dissertation: Deutsche National Bibliothek

Georgios Kotsaris

Doctoral project: Osr1 controls the pro-regenerative response of fi-broadipogenic progenitors

Supervisor of the 2165: Geißler

Dissertation: Deutsche National Bibliothek

Ruth Leben

Doctoral project: Vector-analyzed fluorescence lifetime microscopy approach: new insights into cell metabolism and calcium signaling, in vitro and in vivo

Supervisors of the RU 2165: NiesnerHauser

Dissertation: Deutsche National Bibliothek

Julia Mehl

Doctoral project: Mechanical aspects of extracellular matrix assembly and angiogenesis during bone healing

Supervisors of the RU 2165: Vogel | Duda

Dissertation: ETH Zürich Research Collection

David Reismann

Doctoral project:  Longitudinal intravital multiphoton microendoscopy in the bone marrow of mice / David Reismann

Supervisors of the RU 2165: Hauser | Duda | Niesner

Dissertation: Deutsche National Bibliothek

Paul Rikeit

Doctoral project: The skeleton in the skeleton : on the role of the actin cytoskeleton in BMP signaling in bone / by Paul Philipp Rikeit

Supervisor of the RU 2165: Knaus

Dissertation: Deutsche National Bibliothek

Claudia Schlundt

Doctoral project: Impact of the adaptive immune system in bone fracture healing

Supervisors of the RU 2165: Duda | Volk | Schmidt-Bleek

Dissertation: Deutsche National Bibliothek

Jonathan Stefanowski

Doctoral project: Elucidating the mechanisms of bone regeneration using longitudinal intravital multiphoton endomicroscopy in the murine bone marrow

Supervisors of the RU 2165: Hauser | Duda | Niesner

Dissertation: Deutsche National Bibliothek

Michael Thelen

Doctoral project: Altered bone formation response to mechanical loading in a mouse model of the progeroid disorder gerodermia osteodysplastica

Supervisor of the RU 2165: Kornak

Dissertation: Deutsche National Bibliothek

Sebastian Wendler

Doctoral project: Delayed local delivery of synthetic prostacyclin to modulate inflammatory processes in support of bone regeneration

Supervisors of the RU 2165: Duda | Volk | Schmidt-Bleek

Dissertation: Deutsche National Bibliothek

 

 

 

Founded by the DFG (Project Number: 249509554)
Funding Period 2014-2022